ea0044oc2.1 | Neuroendocrinology and Reproduction | SFEBES2016
Comninos Alexander
, Wall Matthew
, Demetriou Lysia
, Shah Amar
, Clarke Sophie
, Narayanaswamy Shakunthala
, Nesbitt Alexander
, Izzi-Engbeaya Chioma
, Prague Julia
, Abbara Ali
, Ratnasabapathy Risheka
, Salem Victoria
, Nijher Gurjinder
, Jayasena Channa
, Tanner Mark
, Bassett Paul
, Mehta Amrish
, Rabiner Eugenii
, Honigsperger Christoph
, Dhillo Waljit
Kisspeptin is a crucial activator of reproductive function, playing a critical role in the hypothalamus to activate GnRH neurons and downstream reproductive hormones. However, kisspeptin and its receptor are also expressed in other brain areas, yet little is known about their function here. The limbic system plays a key role in sexual and emotional behaviours and has a high expression of kisspeptin receptors. We therefore hypothesised that kisspeptin administration may modulat...